Synthesis and applications of hypervalent iodine compounds and metal organic frameworks

Abstract

Hypervalent iodine reagents have remarkable history as valuable reagents for newlineinnumerable oxidative transformations since the synthesis of first hypervalent iodine newlinecompound; (dichloroiodo)benzene. These reagents served as flipside of toxic heavy newlinemetal oxidants due to their ease of availability, less-toxicity and selectivity. On the newlineother hand, metal-organic frameworks have been found as efficient catalysts in various newlinefields such as sensing, biomedicine, catalysis, adsorption and electrochemical newlineapplications. In this thesis, we delved into synthetic applications of hypervalent iodine newlinereagents and metal-organic frameworks (MOFs). In context to hypervalent iodine newlinereagents, the thesis presents the design and synthesis of some new iodoarenes, newlinefollowed by investigating their catalytic activity towards diverse oxidative newlinetransformations. Besides, some biologically active pyrazole-tethered isoxazoles have newlinebeen synthesized by utilizing diacetoxyiodobenzene in presence of trifluoroacetic acid. newlineAdditionally, the thesis explores the catalytic efficiency of diiodo-precatalysts newlineembedded within MOFs, which exhibit remarkable recyclability in the oxidation of newlinehydroquinone across three cycles. The research also ventures into the field of newlineiodonium salts, detailing the design of new salts and the attempts for their synthesis. newlineOn the MOF front, the synthesis of new cauliflower-like palladium-doped MOF newlinematerials is presented. These palladium-doped MOF material demonstrates its utility newlinein the degradation of dyes and the reduction of nitroaromatic compounds. Notably, the newlinepalladium-loaded MOF material exhibit excellent recyclability in the degradation of newlineCongo red dye and the reduction of 4-nitrophenol. newlineThe findings of this thesis underscore the versatility of hypervalent iodine reagents and newlineMOFs, paving the way for their increased adoption in various fields of chemistry and newlinematerial science. newline